JMCB Symposium 2018: Looking into
Complex Diseases

JMCB Symposium 2018: Looking into Complex Diseases

June 8-10, 2018  Shanghai, China

June 8-10, 2018
 Shanghai, China


Molecular Systems Biology in Complex Diseases

Uttiya Basu (Columbia University, USA)
Title: Gene expression control and genome organization at sites of noncoding RNA surveillance activity
Ralf Elvert (Sanofi-Aventis Deutschland GmbH, Germany)  
Title: The effect of GLP-1 and Glucagon receptor dual agonists on glucose and energy homeostasis: from mice to man
David M. Gilbert (Florida State University, USA) 
Title: Developmental control of replication timing and chromosome architecture
Yumiko Imai (National Institute of Biomedical Innovation, Health and Nutrition, Japan)  
Title: Dynamic changes in host nuclear system to influenza virus infection
Sheng-Cai Lin (Xiamen University, China)  
Title: Glucose sensing and regulation of anabolic/catabolic metabolism
Jiguang Wang (Hong Kong University of Science and Technology, HK)  
Title: Mutational landscape of secondary Glioblastoma reveals MET as a moving target in brain cancer
Yong Wang (Academy of Mathematics and Systems Science, CAS, China)  
Title: Intepretating genetic variants by gene regulatory network
Wing Hung Wong (Stanford University, USA)  
Title: TBA
Rong Zeng (Shanghai Institute of Biochemistry and Cell Biology, CAS, China) 
Title: Systems integration of multi-Omics data to evaluate physiological and pathological status

Genome Instability and DNA Damage in Aging and Cancer

Junjie Chen (The University of Texas MD Anderson Cancer Center, USA)  
Title: Proteomic analysis of DNA damage response and tumorigenesis
Shridar Ganesan (Rutgers Cancer Institute of New Jersey, USA)  
Title: Role of G9a methyltransferase in the DNA repair response/LOHGIC: Analyzing BRCA1/2 pathway alterations using clinical grade sequencing
Stephen Kowalczykowski (University of California, Davis, USA)  
Title: Roles of recombination mediators in genome maintenance  
Li Lan (University of Pittsburgh, USA)  
Title: Insights into Oxidative DNA Damage Responses in coding region of genome
Guang Peng (The University of Texas MD Anderson Cancer Center, USA)  
Title: PARP inhibitors induce immunogenicity through transcriptome reprogramming independent of BRCAness
Lawrence Sowers (The University of Texas Medical Branch, USA)  
Title: How does inflammation drive mutagenesis in colorectal cancer?
Wei Yang (NIDDK, National Institutes of Health, USA)  
Title: Molecular and atomic organization of DNA replication, recombination and repair  
Wenge Zhu (George Washington University School of Medicine and Health Science,USA)   
Title: High-throughput analyses to identify a novel mechanism regulating platinum drug resistance in ovarian cancer
Lee Zou (Harvard Medical School, MGH Cancer Center, USA)  
Title: New roles of ATR in safeguarding the genome

Immunity in Health and Diseases

Alfred L. M. Bothwell (Yale Medical School, USA) 
Title: TBA
Chen Dong (Tsinghua University School of Medicine, China) 
Title: Control of T cell function in immunity, inflammation and cancer
Florent Ginhoux (Singapore Immunology Network, A*Star, Singapore) 
Title: Dendritic cell, monocyte and macrophage biology: from development to functions
Sankar Ghosh (Columbia University Medical Center, USA) 
Title: Regulation of immunoparalysis during sepsis
Huabing Li (Shanghai Jiao Tong University School of Medicine, China) 
Title: RNA m6A in T cell-mediated inflammation
John D. MacMicking (HHMI, Yale Systems Biology Institute, USA) 
Title: TBA
Hai Qi (Tsinghua University School of Medicine, China) 
Title: Cellular dynamics and interactions supporting the germinal center
Bing Su (Shanghai Jiao Tong University School of Medicine, China) 
Title: Dab2 function in inflammation 
Yisong Wan (University of North Carolina, USA) 
Title: The regulation of Th17 cell function and its implication in disease
Qiang Zou (Shanghai Jiao Tong University School of Medicine, China) 
Title: Cross-talk between ROS and Treg cell-mediated tumor immunosuppression

Cell Biology and Disease Modeling in Organoids

Weihang Chai (Washington State University, USA)  
Title: Decoding replication stress-induced fragile site and telomere instability
Shuibing Chen (Weill Cornell Medical College, USA) 
Title: Stem cell-based disease modeling and drug discovery 
Haian Fu (Emory University, USA) 
Title: High-throughput synthetic lethal screening with a genetically engineered 3D organoids system 
Dong Gao (Shanghai Institute of Biochemistry and Cell Biology, CAS, China)
Title: Cancer organoids and targeted therapy 
Pengyu Huang (ShanghaiTech University, China) 
Title: Regulation of liver regeneration during chronic liver injuries 
Geert Kops (Hubrecht Institute, UMC Utrecht, Netherlands)  
Title: Causes and consequences of chromosomal instability in cancer
Leo Price (OcellO, the Netherlands) 
Title: Screening and profiling of (immuno-)oncology therapeutics in primary and stem cell-derived Human 3D Tissues 
Paul Kwong-Hang Tam (The University of Hong Kong, HK) 
Title: Modeling of Hirschsprung's disease in gastric organoids 
Mingjie Zhang (Hong Kong University of Science & Technology, HK) 
Title: Regulation of neurogenesis via modulating kinetochore attachment of Ndel1/Nde1 during mitosis